Ajinomoto Health & Nutrition North America, Inc.

Ajinomoto Health & Nutrition North America, Inc.

BioPharmaceutical

For the best end products, start with the best ingredients.

Pharmaceutical Grade Amino Acids

Our complete line of multi compendial-grade amino acids is ideal for use in mammalian cell culture media, excipients or as an API.

Ajinomoto Biopharma bottling process

The Ajinomoto Difference

The best amino acids, from start to finish.

State of the Art Fermentation Process

Ajinomoto was the first company in the world to manufacture amino acids using fermentation. Today we deliver the highest quality amino acids available.

Manufacturing & Packaging

We provide a range of packaging options to meet your specifications — from 50kg bulk containers to small quantities available in 1kg and 10kg packs that are ideal for research, development and clinical studies.

Quality Research & Development

We are committed to continued advances in amino acid research, development and manufacturing to ensure you always have the highest-quality products to meet your evolving needs and customer demands.

Resources to Support Your Business

Our applications support many aspects of this industry.

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Specifications

We manufacture amino acids to the highest standards of purity and quality. Which means we’re registered by, compliant with or certified by all the appropriate quality standards: cGMP, JP, USP, EP, DMF, JDMF, CEP, ICH, CFR and ISO. And that’s just for starters — because we maintain our own internal benchmarks that are, quite simply, second to none.

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Milling & Blending

With our cGMP blending and pulverization services, we can produce amino acid blends to your exact specifications – so you can optimize production space, decrease analytical testing and improve inventory management.

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Manufacturing & Packaging

Part of our job is to make your job as easy as possible. So once we create top-quality amino acids using our advanced fermentation manufacturing process and patented production technology, we make them available to you in the quantities you need. In addition to Standard Bulk packaging — 20 kg, 25 kg and 50 kg sizes — we offer exactly the same pharmaceutical-grade amino acids in smaller 1 kg and 10 kg polyvinyl pails for R&D, product and process development and clinical trials.

Ajinomoto Amino Acids

Ajinomoto can support your every project from biotech, injectables and enterics to health foods, nutrition products and food additives.

Glycine

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Alanine

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Alanyl-L-Glutamine

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Arginine

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Arginine HCl

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Aspartic Acid

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Cysteine

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Cysteine HCl Anhy

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Cystine

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Cystine 2HCl

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Glutamine

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Levodopa

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Glutamic Acid

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Histidine

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Histidine HCl H2O

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Isoleucine

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Leucine

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Lysine Acetate

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Lysine HCl

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Methionine

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Phenylalanine

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Proline

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Serine

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Threonine

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Tryptophan

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Tyrosine

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Valine

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Featured Products

Pharma-Grade Amino Acids

The highest quality ingredients for your pharmaceutical grade products.

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GLYCINE

Abbreviation Gly
Chemical Name Aminoacetic Acid
Chemical Formula C2H5NO2
Molecular Weight 75.07
Nitrogen Content 18.66%
CAS Number 56-40-6
Conforms To USP, EP, JP
Solubility Freely soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder; sweet taste
Country of Origin USA: Sourced by Ajinomoto
Manufacturing Process Enzymatic
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Glycine, a non-essential amino acid, is a component of antioxidant glutathione and is used in pharmaceuticals for treating eczema and dermatitis. It is found in parenteral and enteral nutrition and in many foods as a seasoning or natural preservative due to its antimicrobial properties.

L-ALANINE

Abbreviation L-Ala
Chemical Name (S)-2-Aminopropionic Acid
Chemical Formula C3H7NO2
Molecular Weight 89.09
Nitrogen Content 15.72%
CAS Number 56-41-7
Conforms To USP, EP, JP
Solubility Freely soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder; slightly sweet to taste
Country of Origin USA, China
Manufacturing Process Enzymatic
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Alanine is a non-essential amino acid that participates in the TCA cycle; metabolizing to glucose in the liver. It is a component in parenteral and enteral nutrition, as an active pharmaceutical ingredient and in foods as both a nutritional and flavoring compound.

ALANYL-L-GLUTAMINE

Abbreviation Ala-Gln
Chemical Name L-Alanyl-L-Glutamine
Chemical Formula C8H15N3O4
Molecular Weight 217.22
Nitrogen Content 19.30%
CAS Number 39537-23-0
Assay 97.0 to 103.0%
Description White crystals or crystalline powder
Country of Origin USA
Manufacturing Process Fermentation
Packaging 500 g, 5 Kg poly pail, 20 Kg fiber drum
Additional Information Alanyl-L-Glutamine is a dipeptide of L-Alanine and L-Glutamine that creates a stable source of L-Glutamine that does not degrade in solution, improving solubility and flavor.

L-ARGININE

Abbreviation L-Arg
Chemical Name (2S)-2-Amino-5-guanidinopentanoic Acid
Chemical Formula C6H14N4O2
Molecular Weight 174.20
Nitrogen Content 32.16%
CAS Number 74-79-3
Conforms To USP, EP, JP
Solubility Freely soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder
Country of Origin Japan
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Arginine, considered a non-essential amino acid for adults, is essential for infants because they have not yet acquired a sufficient capacity for in-vivo synthesis. Arginine is in parenteral and enteral nutrition and because of its natural moisturizing ability; it is useful in the formulation of cosmetic creams shampoos and rinses.

L-ARGININE HCL

Abbreviation L-Arg HCL
Chemical Name (2S)-2-Amino-5-guanidinopentanoic Acid Monohydrochloride
Chemical Formula C6H14N4O2·HCl
Molecular Weight 210.66
Nitrogen Content 26.60%
CAS Number 1119-34-2
Conforms To USP, EP, JP
Solubility Freely soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder
Country of Origin Japan, China
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Arginine HCl, a non-essential amino acid, is a unique precursor of nitrogen monoxide (NO) and vasodilator. Arginine HCl has higher solubility and less characteristic taste and odor than arginine.

L-ASPARTIC ACID

Abbreviation L-Asp
Chemical Name (S)-Aminosuccinic Acid
Chemical Formula C4H7NO4
Molecular Weight 133.10
Nitrogen Content 10.52%
CAS Number 56-84-8
Conforms To USP, EP, JP
Solubility Slightly soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder
Country of Origin Pharma grade: Japan, Food grade: France
Manufacturing Process Enzymatic
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Aspartic Acid is a non-essential amino acid found in abundance in plant proteins and is manufactured in the body from oxaloacedic acids. Both aspartic acid and glutamic acid play important roles as general acids in enzyme active centers, as well as in maintaining the solubility and ionic character of proteins.

L-CYSTEINE

Abbreviation L-Cys
Chemical Name (R)-2-Amino-3-mercaptopropionic Acid
Chemical Formula C3H7NO2S
Molecular Weight 121.16
Nitrogen Content 11.56%
CAS Number 52-90-4
Conforms To DAB
Solubility Freely soluble in water
Assay 98.0 to 101.0%
Description White crystals or crystalline powder; characteristic taste
Country of Origin Japan
Manufacturing Process Fermentation
Packaging 1 kg poly drum, 20 kg fiber box
Additional Information Cysteine, a non-essential amino acid, is a precursor to taurine and a component of antioxidant glutathione. Improves hepatic function and used in amino acids infusions, as a flavoring component, bread fermentation supplement and as an antioxidant for natural fruit juice products.

L-CYSTEINE HCL ANHYDROUS

Abbreviation L-Cys HCl
Chemical Name (R)-2-Amino-3-mercaptopropionic Acid Monohydrochloride52-
Chemical Formula C3H7NO2S·HCl
Molecular Weight 157.62
Nitrogen Content 8.88%
CAS Number 52-89-1
Solubility Very soluble in water
Assay 98.0 - 102.0%
Description White crystals or crystalline powder, strong acid taste
Country of Origin Japan
Manufacturing Process Fermentation
Packaging 1kg poly drum, 20kg fiber box
Additional Information Cysteine HCl Anhydrous is a non-essential amino acid. It is a precursor to taurine and a component of antioxidant glutathione. Improves hepatic function and used in amino acids infusions, as a flavoring component, bread fermentation supplement and as an antioxidant for natural fruit juice products.
Additional Information Cysteine, a non-essential amino acid, is a precursor to taurine and a component of antioxidant glutathione. Improves hepatic function and used in amino acids infusions, as a flavoring component, bread fermentation supplement and as an antioxidant for natural fruit juice products.

L-CYSTINE

Abbreviation L-Cys2
Chemical Name 3,3’ –Disulfanediylbis (2R)-2-aminopropanoic acid
Chemical Formula C6H12N2O4S2
Molecular Weight 240.30
Nitrogen Content 11.66%
CAS Number 56-89-3
Conforms To EP
Solubility Practically insoluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder; tasteless
Country of Origin Japan
Manufacturing Process Fermentation
Packaging Not available
Additional Information Cystine is a non-essential amino acid that is produced by methionine in the body. It is necessary for the formation of skin, promotes healing from skin traumas and stimulates formation of white and red blood cells.

L-CYSTINE 2HCL

Abbreviation L-Cys 2HCL
Chemical Name L-(-)-Cystine DiHydrochloride
Chemical Formula C6H12N2O4S2·HCl
Molecular Weight 313.22
Nitrogen Content 8.94%
CAS Number 30925-07-6
Solubility Freely soluble in Dilute hydrochloric acid
Assay 98.0% to 102.0%
Description White to pale yellow crystalline powder
Country of Origin USA: Sourced by Ajinomoto
Manufacturing Process Fermentation
Packaging Not available
Additional Information Cystine 2HCl is a non-essential amino acid and is necessary for the formation of skin, promotes healing from skin traumas and stimulates formation of white and red blood cells. Commonly used in cell culture media because it is more soluble than cystine base.
Additional Information Cystine is a non-essential amino acid that is produced by methionine in the body. It is necessary for the formation of skin, promotes healing from skin traumas and stimulates formation of white and red blood cells.

L-GLUTAMINE

Abbreviation L-Gln
Chemical Name (S)-2-Aminoglutaramic Acid
Chemical Formula C5H10N2O3
Molecular Weight 146.14
Nitrogen Content 19.17%
CAS Number 56-85-9
Conforms To USP, JP, DAB
Solubility Soluble in water
Assay 99.0 to 101.0%
Description White crystals or crystalline powder; slightly characteristic taste
Country of Origin Brazil
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 25 kg fiber drum
Additional Information Glutamine, nutritionally classified as a non-essential amino acid, has a profound involvement in the way that animals and plants maintain their nitrogen levels and in ammonia detoxification. Glutamine is a protein-building amino acid that is important for maintaining muscle as well as supporting immune and intestinal health.

LEVODOPA

Abbreviation L-DOPA
Chemical Name (S)-(3,4-Dihydroxyphenyl) Alanine
Chemical Formula C9H11NO4
Molecular Weight 197.19
Nitrogen Content 7.10%
CAS Number 59-92-7
Conforms To USP, EP
Solubility Slightly soluble in water
Assay 98.0% to 102.0%
Description White to slightly off-white crystals or crystalline powder
Country of Origin Japan
Manufacturing Process Enzymatic
Packaging 500 g, 10 kg poly pail, 50 kg fiber drum
Additional Information Levodopa is manufactured by the enzymatic method from catechol and pyruvic acid or by chemical synthesis using vanillin as the starting material. It is the main active pharmaceutical ingredient for the treatment of Parkinson's disease.

L-GLUTAMIC ACID

Abbreviation L-Glu
Chemical Name (S)-2-Aminoglutaric Acid
Chemical Formula C5H9NO4
Molecular Weight 147.13
Nitrogen Content 9.52%
CAS Number 56-86-0
Conforms To EP
Solubility Slightly soluble in water
Assay 99.0% to 100.5%
Description White crystals or crystalline powder, slightly characteristic taste
Country of Origin Pharma grade: Japan, Food grade: Brazil
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 50 kg fiber drum
Additional Information Glutamic Acid is a non-essential amino acid and functions as an important neurotransmitter and as a metabolic intermediate in the Krebs cycle. It is a primary component of the savory flavor umami. Both aspartic acid and glutamic acid play important roles as general acids in enzyme active centers, as well as in maintaining the solubility and ionic character of proteins.

L-HISTIDINE

Abbreviation L-His
Chemical Name (S)-2-Amino-1H-imidazole-4-propionic Acid
Chemical Formula C6H9N3O2
Molecular Weight 155.15
Nitrogen Content 27.08%
CAS Number 71-00-1
Conforms To USP, EP, JP
Solubility Soluble in water
Assay 99.0% to 101.0%
Description White crystals or crystalline powder; slightly bitter taste
Country of Origin USA
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Histidine is an essential amino acid and plays a key role in production of red and white blood cells. It can be used in parenteral and enteral nutrition, and in the food industry as a supplement, seasoning and flavoring substance.

L-HISTIDINE HCL H2O

Abbreviation L-His HCl H2O
Chemical Name (2)-2-Amino-1H-imidazole-4-propionic Acid Monohydrochloride Monohydrate
Chemical Formula C6H9N3O2·HCl·H2O
Molecular Weight 209.63
Nitrogen Content 20.04%
CAS Number 5934-29-2
Conforms To EP, JP
Solubility Freely soluble in water
Assay 99.0% to 101.0%
Description White crystals or crystalline powder; slightly acid and bitter taste
Country of Origin USA
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 50 kg fiber drum
Additional Information Histidine HCl H2O is an essential amino acid playing a key role in production of red and white blood cells. It can be used in parenteral and enteral nutrition, and in the food industry as a supplement, seasoning and flavoring substance. It is manufactured by neutralizing L-histidine with hydrochloric acid.

L-ISOLEUCINE

Abbreviation L-Ile
Chemical Name (2S, 3S)-2-Amino-3-methylpentanoic Acid
Chemical Formula C6H13NO2
Molecular Weight 131.17
Nitrogen Content 10.68%
CAS Number 73-32-5
Conforms To USP, EP, JP
Solubility Sparingly soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder; slightly bitter taste
Country of Origin Brazil, China
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 25 kg fiber drum
Additional Information Isoleucine is an essential amino acid that is commonly used in parenteral and enteral nutrition. It is used in combination with the other branched chain amino acids (Leucine and Valine) to serve as important fuel sources for skeletal muscle during periods of metabolic stress.

L-LEUCINE

Abbreviation L-Leu
Chemical Name (2S)-2-Amino-4-methylpentanoic Acid
Chemical Formula C6H13NO2
Molecular Weight 131.17
Nitrogen Content 10.68%
CAS Number 61-90-5
Conforms To USP, EP, JP
Solubility Sparingly soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder; slightly bitter taste
Country of Origin Pharma grade: USA, China, Food grade: Brazil
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Leucine, an essential amino acid, is one of the branched chain amino acids (BCAAs) that is used as an important component of sports nutrition and health foods to increase energy, enhance endurance and aid in muscle recovery. Leucine can also be used as a flavoring substance and as a lubricant for tablet production.

L-LYSINE ACETATE

Abbreviation L-Lys-AcOH
Chemical Name (2S)-2. 6-Diaminohexanoic acid monoacetate
Chemical Formula C6H14N2O2·C2H4O2
Molecular Weight 206.24
Nitrogen Content 13.58%
CAS Number 57282-49-2
Conforms To USP, EP
Solubility Very Soluble in water and in formic acid
Assay 98.5% to 101.0%
Description White crystals or crystalline powder; slightly acid taste
Country of Origin USA
Manufacturing Process Fermentation
Packaging 1 kg poly pail, 50 kg fiber drum
Additional Information Lysine Acetate is an essential amino acid. The lysine content of vegetable protein is generally low; therefore, vegetarians may need to supplement lysine in their diet. Hair care products such as shampoos and rinses use Lysine as an excipient.

L-LYSINE HCL

Abbreviation L-Lys HCl
Chemical Name (2S)-2, 6-Diaminohexanoic Acid Monohydrochloride
Chemical Formula C6H14N2O2·HCl
Molecular Weight 182.65
Nitrogen Content 15.34%
CAS Number 657-27-2
Conforms To USP, EP, JP
Solubility Freely soluble in water
Assay 98.5 to 101.0%
Description White powder; slightly characteristic taste
Country of Origin China
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 40 kg fiber drum
Additional Information Lysine HCl is an essential amino acid. The lysine content of vegetable protein is generally low; therefore, vegetarians may need to supplement lysine in their diet. Hair care products such as shampoos and rinses use Lysine as an excipient. L-lysine HCl is obtained by neutralizing with hydrochloric acid.

L-METHIONINE

Abbreviation L-Met
Chemical Name (2S)-2-Amino-4-(methylsulfanyl) Butanoic Acid
Chemical Formula C5H11NO2·S
Molecular Weight 149.21
Nitrogen Content 9.39%
CAS Number 63-68-3
Conforms To USP, EP, JP
Solubility Soluble in water
Assay 99.0 tp 101.0%
Description White crystals or crystalline powder; characteristic odor
Country of Origin Japan: Sourced by Ajinomoto
Manufacturing Process Enzymatic
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Methionine is an essential amino acid and critical to phospholipid metabolism. It can be a component in infant formula, sports supplements and a flavoring substance.

L-PHENYLALANINE

Abbreviation L-Phe
Chemical Name (2S)-2-Amino-3-phenylpropanoic Acid
Chemical Formula C9H11NO2
Molecular Weight 165.19
Nitrogen Content 8.48%
CAS Number 63-91-2
Conforms To USP, EP, JP
Solubility Sparingly soluble in water
Assay 98.5 tp 101.0%
Description White crystals or crystalline powder; slightly bitter taste
Country of Origin Japan, China
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Phenylalanine is an essential amino acid derived from animal and vegetable proteins and deficiencies are very rare. However, in some rare cases, an inborn error in metabolism known as Phenylketonuria (PKU) can cause Phenylalanine to build up in the blood, resulting in a lifelong diet that is low in Phenylalanine.

L-PROLINE

Abbreviation L-Pro
Chemical Name (S)-2-Pyrrolidinecarboxylic Acid
Chemical Formula C5H9NO2
Molecular Weight 115.13
Nitrogen Content 12.17%
CAS Number 147-85-3
Conforms To USP, EP, JP
Solubility Very Soluble in water
Assay 99.0% to 101.0%
Description White crystals or crystalline powder; slightly sweet taste
Country of Origin USA
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Proline is a non-essential amino acid but an essential component of collagen and is important for proper functioning of joints and tendons. It is a component in parenteral and enteral nutrition, cosmetics, health foods and flavoring.

L-SERINE

Abbreviation L-Ser
Chemical Name (S)-2-Amino-3-hydroxypropionic Acid
Chemical Formula C3H7NO3
Molecular Weight 105.09
Nitrogen Content 13.33%
CAS Number 56-45-1
Conforms To USP, EP, JP
Solubility Freely soluble in water
Assay 98.5% to 101.0%
Description White crystals or crystalline powder; slightly sweet taste
Country of Origin USA
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Serine is classified as a non-essential amino acid. The body can synthesize sufficient amounts of serine to meet its daily needs. Serine and products of its metabolism are essential for cell proliferation and specific functions of the central nervous system.

L-THREONINE

Abbreviation L-Thr
Chemical Name (2S,3R)-2-Amino-3-hydroxybutanoic Acid
Chemical Formula C4H9NO3
Molecular Weight 119.12
Nitrogen Content 11.76%
CAS Number 72-19-5
Conforms To JP, USP, EP
Solubility Soluble in water
Assay 99.0 to 101.0%
Description White crystals or crystalline powder; slightly sweet taste
Country of Origin USA
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 50 kg fiber drum
Additional Information Threonine is an essential amino acid metabolized to form other amino acids such as glycine and serine. It is a key component of collagen, enamel proteins and aids in proper fat metabolism in the liver; nutrients are more readily absorbed when threonine is present.

L-TRYPTOPHAN

Abbreviation L-Trp
Chemical Name (2S)-2-Amino-3-(indol-3-yl) Propanoic Acid
Chemical Formula C11H12N2O2
Molecular Weight 204.23
Nitrogen Content 13.72%
CAS Number 73-22-3
Conforms To USP, EP, JP
Solubility Slightly soluble in water
Assay 99.0 to 101.0%
Description White to yellowish white crystals, or crystalline powder
Country of Origin USA
Manufacturing Process Fermentation
Packaging 500 grams, 10 Kg poly pail, 25 Kg fiber drum
Additional Information Tryptophan is an essential amino acid that is required to maintain appropriate levels of serotonin and melatonin. It is used in parenteral and enteral nutrition and is an active ingredient in many antidepressants, hypnotics and natural sleep aids.

L-TYROSINE

Abbreviation L-Tyr
Chemical Name (S)-2-Amino-3-(4-hydroxyphenyl) Propionic Acid
Chemical Formula C9H11NO3
Molecular Weight 181.19
Nitrogen Content 7.73%
CAS Number 60-18-4
Conforms To USP, EP, JP
Solubility Practically insoluble in water
Assay 99.0% to 101.0%
Description White crystals or crystalline powder; tasteless
Country of Origin Japan
Manufacturing Process Fermentation
Packaging 1 kg, 10 kg poly pail, 25 kg fiber drum
Additional Information Tyrosine is a non-essential amino acid. It is a precursor to dopamine and other adrenomedullary hormones, an important factor in regulating mood. Tyrosine is involved in the metabolism of the amino acid phenylalanine and has been used to ease headaches, stress, anxiety and chemical addictions.

L-VALINE

Abbreviation L-Val
Chemical Name (2S)-2-Amino-3-Methylbutanoic Acid
Chemical Formula C5H11NO2
Molecular Weight 117.15
Nitrogen Content 11.96%
CAS Number 72-18-4
Conforms To USP, EP, JP
Solubility Soluble in water
Assay 98.5 to 101.0%
Description White crystals or crystalline powder
Country of Origin Pharma grade: USA, China, Food grade: Brazil
Manufacturing Process Fermentation
Packaging 1 Kg, 10 Kg poly pail, 50 Kg fiber drum
Additional Information Valine is an essential amino acid and one of the three branched chain amino acids (BCAA). As a branched chain amino acid, valine is important for optimal growth in infants and children and nitrogen balance in adults. Valine is key in parenteral and enteral nutrition and in health food supplements.